CHANLAB

Dr. Anuj Yadav

PhD in Chemistry, NCL India

Postdoc, SFU

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Publications

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15. Bandyopadhyay S, Zhao Z, East AK, Tapia Hernandez R, Forzano JA, Shapiro BA, Yadav AK, Swartchick CB, Chan J.* An activity-based nitric oxide-responsive porphyrin for site-selective and nascent cancer ablation. ACS Appl. Mater. Interfaces. 2024, 16, 8, 9680–9689.

 

14. Zhao Z, Yadav AK, Weng Y, Chan J. Development of nitroreductase-activatable fluoroquinolone prodrugs exhibiting attenuated magnesium ion binding. Helv. Chim. Acta. 2023, 106, 10, e202300100.

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13. Yadav AK, Chan J. Activity-based bioluminescence probes for in vivo sensing applications. Curr. Opin. Chem. Biol. 2023, 74, 102310.

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12. Yadav AK, Zhao Z, Weng Y, Gardner SH, Brady CJ, Pichardo Peguero OD, Chan J. Hydrolysis-resistant ester-based linkers for development of activity-based NIR bioluminescence probes. J. Am. Chem. Soc. 2023, 145, 2, 1460–1469.

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11. Tapia Hernandez R, Lee MC, Yadav AK, Chan J. Repurposing cyanine photo-instability to develop NIR light-activatable nanogels for in vivo cargo delivery. J. Am. Chem. Soc. 2022, 144, 18101–18108.

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10. Lucero MY, Gardner SH, Yadav AK, Borri A, Zhao Z, Chan J. Activity-based photoacoustic probes reveal elevated intestinal MGL and FAAH activity in a murine model of obesity. Angew. Chem. Int. Ed. 2022, 61, e202211774.

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9. Yadav AK, Lee MC, Lucero MY, Reinhardt, CJ, Su S, Chan J. NIR bioluminescence probe enables discovery of diet-induced modulation of tumor microenvironment via nitric oxide. ACS Cent. Sci. 2022, 8, 461-472.

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8. Gardner SH, Brady CJ, Keeton C, Yadav AK, Mallojjala SC, Lucero MY, Su S, Yu Z, Hirschi JS, Mirica LM, Chan J. A general approach to convert hemicyanine dyes into highly optimized photoacoustic scaffolds for analyte sensing. Angew. Chem. Int. Ed. 2021, 60, 18860–18866.

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7. Yadav AK, Tapia Hernandez R, Chan J. A general strategy to optimize the performance of aza-BODIPY-based probes for enhanced photoacoustic properties. Methods in Enzymology, 2021, 657, 415-441.

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6. Yadav AK, Hernandez S, Su S, Chan J. Acoustic-based chemical tools for profiling the tumor microenvironment. Curr. Opin. Chem. Biol. 2020, 57, 114-121.

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5. Yadav AK, Reinhardt CJ, Arango AS, Huff HC, Dong L, Malkowski MG, Das A, Tajkhorshid E, Chan J. An Activity-based sensing approach for the detection of cyclooxygenase-2 in live cells. Angew. Chem. Int. Ed. 2020, 59, 3307-3314.

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4. Yadav AK, Chan J. Bright dyes bring biology into focus. ACS Cent. Sci. 2017, 3, 920-921.

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3. Abadi SSK, Tran M, Yadav AK, Adabala PJP, Chakladar S, Bennet AJ. New Class of Glycoside Hydrolase Mechanism-Based Covalent Inhibitors: Glycosylation Transition State Conformations. J. Am. Chem. Soc. 2017, 139, 10625-10628.

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2. Perley-Robertson GE, Yadav AK, Winogrodzki JL, Stubbs KA, Mark BL, Vocadlo DJ. A fluorescent transport assay enables studying AmpG Permeases involved in peptidoglycan recycling and antibiotic resistance. ACS Chem. Biol. 2016, 11, 2626-2635.

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1. Yadav AK, Shen DL, Shan X, He X, Kermode AR, Vocadlo DJ. Fluorescence-quenched substrates for live cell imaging of human glucocerebrosidase activity. J. Am. Chem. Soc. 2015, 137, 1181-1189.

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Select Awards

2. C.S. Marvel Travel Award (2021)

1. TiMe Day Outstanding Research Poster Award (2019)​